AKL2 - Cystic Fibrosis, an hereditary disease starting in infancy that affects various glands and results in secretion of thick mucus that blocks internal passages, including those of the lungs, causing respiratory infections. The pancreas is also affected, resulting in a deficiency of digestive enzymes and impaired nutrition.
 
Airway mucus is a complex mixture of secretory products that provides a multifaceted defence against pulmonary infection. Mucus contains antimicrobial peptides (e.g., defensins) and enzymes (e.g., lysozyme).
 
Mucous hypersecretion is a hallmark of chronic airway diseases, including cystic fibrosis: Goblet cell hyperplasia and persistence are characteristic pathologic features. In asthmatics, 20–25% of airway epithelial cells are goblet cells.
 
We believe that AKL II ameliorates excessive mucous production in cystic fibrosis. Please contact us for further information.